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# Genie News

# April 3, 2024

  • Public Release 15.1 of AACR Project GENIE:
    • The public release 15.1 version of AACR GENIE has 61 samples retracted that were present in AACR GENIE 15.0-public.
    • More detailed information can be found in the AACR GENIE release notes and the data releases page from Sage Bionetworks.

# January 9, 2024

  • Public Release 15.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The current release, GENIE 15.0-public now contains over 198,000 sequenced samples from over 172,000 patients, making the AACR Project GENIE registry among the largest fully public cancer genomic data sets.
    • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.

# November 9, 2023

  • Public Release 14.1 of AACR Project GENIE:
    • The public release 14.1 version of AACR GENIE has 10 samples retracted that were present in AACR GENIE 14.0-public.
    • More detailed information can be found in the AACR GENIE release notes and the data releases page from Sage Bionetworks

# September 20, 2023

  • Public Release 14.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The current release, GENIE 14.0-public now contains 183,000 sequenced samples from nearly 160,000 patients, making the AACR Project GENIE registry among the largest fully public cancer genomic data sets released to date.
    • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.

# May 1, 2023

  • Public Release 13.1 of AACR Project GENIE:
    • The public release 13.1 version of AACR GENIE has 65 samples retracted that were present in AACR GENIE 13.0-public.
    • More detailed information can be found in the AACR GENIE release notes and the data releases page from Sage Bionetworks

# January 9, 2023

  • Public Release 13.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The current release, GENIE 13.0-public now contains more than 167,000 sequenced samples from over 148,000 patients, making the AACR Project GENIE registry among the largest fully public cancer genomic data sets released to date.
    • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.

# November 3, 2022

  • Public Release BPC CRC 2.0-PUBLIC
    • The GENIE BPC CRC v2.0-public dataset contains 1,485 CRC patients from three institutions: MSKCC, DFCI, and VICC.
    • The complete, post-processed data are available on Synapse

# July 6, 2022

  • Public Release GENIE ERBB2 Cohort
    • The study contains 315 samples from 135 patients from 6 institues.

# July 22, 2022

  • Public Release 12.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The current release, GENIE 12.0-public, was released in July 2022.The registry now contains more than 154,000 sequenced samples from 137,000+ patients, making the AACR Project GENIE registry among the largest fully public cancer genomic data sets released to date.
    • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.

# May 19, 2022

  • Public Release BPC NSCLC 2.0-PUBLIC
    • The GENIE BPC NSCLC v2.0-public dataset contains 1,846 NSCLC patients from 4 institutions: MSKCC, DFCI, VICC and UHN.
    • The complete, post-processed data are available on Synapse

# January 7, 2022

  • Public Release 11.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The current release, GENIE 11.0-public, was released in January 2022. The registry now contains over 136,000 sequenced samples from over 121,000 patients, making the AACR Project GENIE registry among the largest fully public cancer genomic data sets released to date.
    • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.

# June 22, 2021

  • Public Release 10.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The tenth data set, GENIE 10.0-public, was released in June 2021. With the most recent data release, the registry now contains genomic information from 120953 samples.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.

# February 8, 2021

  • Public Release 9.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The ninth data set, GENIE 9.0-public, was released in February 2021. With the most recent data release, the registry now contains genomic information from more nearly 17,000 non-small cell lung carcinomas, and nearly 12,000 breast and more than 11,000 colorectal cancers.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.

# July 7, 2020

  • Public Release 8.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The eighth data set, GENIE 8.0-public, was released in July 2020. The combined data set now includes nearly 96,000 de-identified genomic records collected from patients who were treated at each of the consortium's 19 participating institutions, making it among the largest fully public cancer genomic data sets released to date. The combined data set now includes data for over 80 major cancer types, including data from greater than 14,000 patients with lung cancer, nearly 12,000 patients with breast cancer, and nearly 9,500 patients with colorectal cancer.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.
  • For frequently asked questions, visit the AACR FAQ page.

# January 29, 2020

  • Public Release 7.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The seventh data set, GENIE 7.0-public, was released in January 2020. The combined data set now includes nearly 79720 de-identified genomic records collected from patients who were treated at each of the consortium's participating institutions, making it among the largest fully public cancer genomic data sets released to date. The combined data set now includes data for over 80 major cancer types.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.
  • For frequently asked questions, visit the AACR FAQ page.

# July 13, 2019

  • Public Release 6.1 of AACR Project GENIE:
    • The sixth data set, GENIE 6.0-public, was released in early July 2019. A patch to GENIE 6.0-public, GENIE 6.1-pubic, was subsequently released on July 13, 2019. The combined data set now includes nearly 70,000 de-identified genomic records collected from patients who were treated at each of the consortium's participating institutions, making it among the largest fully public cancer genomic data sets released to date. The combined data set now includes data for nearly 80 major cancer types, including data from nearly 11,000 patients with lung cancer, greater than 9,700 patients with breast cancer, and nearly 7,000 patients with colorectal cancer.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.
  • For frequently asked questions, visit the AACR FAQ page.

# July 08, 2019

  • Public Release 6.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The sixth data set, GENIE 6.0-public, was released in July 2019 adding more than 11,000 records to the database. The combined data set now includes nearly 71,000 de-identified genomic records collected from patients who were treated at each of the consortium's participating institutions, making it among the largest fully public cancer genomic data sets released to date. The combined data set now includes data for over 80 major cancer types, including data from greater than 11,000 patients with lung cancer, nearly 9,800 patients with breast cancer, and more than 7,000 patients with colorectal cancer.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.
  • For frequently asked questions, visit the AACR FAQ page.

# January 11, 2019

  • Public Release 5.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The forth data set, GENIE 4.0-public, was released in July 2018 adding more than 7,800 records to the database. The combined data set now includes more than 59,000 de-identified genomic records collected from patients who were treated at each of the consortium's participating institutions, making it among the largest fully public cancer genomic data sets released to date. This data will be released to the public every six months.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.
  • For frequently asked questions, visit the AACR FAQ page.

# July 16, 2018

  • Public Release 4.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The forth data set, GENIE 4.0-public, was released in July 2018 adding more than 7,800 records to the database. The combined data set now includes more than 47,000 de-identified genomic records collected from patients who were treated at each of the consortium's participating institutions, making it among the largest fully public cancer genomic data sets released to date. This data will be released to the public every six months. The public release of the fifth data set, GENIE 5.0-public, will take place in January, 2019.
    • The combined data set now includes data for over 80 major cancer types, including data from greater than 7,500 patients with lung cancer, nearly 5,500 patients with breast cancer, and more than 5,100 patients with colorectal cancer.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.
  • For frequently asked questions, visit the AACR FAQ page.

# January 2018

  • Added 7500 samples to the GENIE Public Cohort The combined dataset now includes samples from over 60 major cancer types including:
    • 6,000 lung cancer samples.
    • 4,500 breast cancer samples.
    • 4,300 colorectal cancer samples.
  • More detailed information can be found in the AACR GENIE Data Guide. In addition to accessing the data via the cBioPortal, users can download the data directly from Sage Bionetworks. For frequently asked questions, visit the AACR FAQ page.

# November 20, 2017

  • Public Release 2.0 of AACR Project GENIE:
    • The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was released to the global community in January 2017. The second dataset was released in November 2017, adding more than 13,000 records to the database. The combined data set now includes over 32,000 de-identified genomic records collected from patients who were treated at each of the consortium’s participating institutions, making it among the largest fully public cancer genomic data sets released to date. These data will be continuously updated on a quarterly basis.
    • The combined data set now includes data for 59 major cancer types, including data on nearly 5,000 patients with lung cancer, nearly 4,000 patients with breast cancer, and more than 3,500 patients with colorectal cancer. For more details about the data, and how to use it, consult the data guide.
    • In addition to accessing the data on the AACR Project GENIE cBioPortal website, users can download the data directly from Sage Bionetworks. Users will need to create an account for either site and agree to the terms of access.
    • For frequently asked questions, visit the AACR FAQ page.

# January 5, 2017

  • Initial public release of AACR Project GENIE:
    • Somatic alterations in 18,980 tumor samples from 18,500 patients sequenced at eight different institutions.
    • Data is available for download from Sage Bionetworks.

# AACR Project GENIE cBioPortal Terms of Use

  • I will not attempt to identify or contact individual participants from whom these data were collected by any means.
  • I will not redistribute the data without express written permission from the AACR Project GENIE Coordinating Center (info at aacrgenie dot org).
  • When publishing or presenting work using or referencing the AACR Project GENIE dataset please include the following attributions:
    • Please cite: AACR Project GENIE Consortium. AACR Project GENIE: Powering Precision Medicine Through an International Consortium, Cancer Discov. 2017 Aug;7(8):818-831 and include the version of the dataset used.
    • Include the following acknowledgement: The authors would like to acknowledge the American Association for Cancer Research and its financial and material support in the development of the AACR Project GENIE registry, as well as members of the consortium for their commitment to data sharing. Interpretations are the responsibility of study authors.
  • Should you decide at any point in the future to stop using the AACR Project GENIE cBioPortal, send request: genie-cbioportal-access at cbio dot mskcc dot org and we will remove your user id and any other information provided during new user registration from our systems.
  • For more information see terms of access on the AACR website.

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